Gentamycyna 5% Inj.


Solution for injection for dogs and cats



Qualitative and quantiative composition of active substance
Gentamicin (in the form of gentamicin sulphate)        50 mg/ml

Therapeuthic indications
Treatment of diseases induced by bacteria sensitive to gentamicin, especially respiratory infections, urogenital infections, skin inflammations, arthral diseases, otitis, infections of the alimentary tract. 

Gentamicin is active against: Pasteurella multocida, Pseudomonas aeruginosa, Klebsiella sp., Escherichia coli, Salmonella sp., Staphylococcus sp.  Campylobacter sp., Mycoplasma sp., Proteus sp.

Pregnancy. Renal insufficiency. Allergy to aminoglycoside antibiotics.

Adverse effects
Long-lasting administration or use of high doses of gentamicin may lead to damage to kidneys or the organ of hearing. Intracanal administration may induce inflammation of the nerve roots of the medulla, fever and chronic pleocytosis.

A proper veterinary surgeon, the Marketing Authorisation Holder or the Office for Registration of Medicinal Products, Medical Devices and Biocidal Products should be notified of any occurrence of adverse effects after administration of the product or observation of any alarming symptoms not listed in the leaflet (including symptoms in people as a result of contact with the drug). The notice form has to be downloaded from the website (The Department of Veterinary Medicinal Products).

Posology and routes of administration
Gentamicin is administered subcutaneously and intramuscularly in a dose of 0.8 ml/10 kg b.w. (which corresponds to 4 mg/kg b.w.)

- on the first day of treatment the drug is administered every 12 hours

- next days – once daily every 24 hours.

This antibiotic is generally administered within 4-5 days. In justified cases longer, e.g. in urinary infections 7-10 days. Alkalisation of urine increases the activity of the antibiotic.

Recommendations for proper administration

Waiting period
Not applicable.

Special precautions for storage and transport
Keep out of the sight and reach of children. Store at a temperature below 25°C. Protect from light. Do not freeze. Use within 28 days after the first opening of the package. Do not use after the expiry date given on the label.

Special warnings and precautions
Young animals, in which the process of renal elimination of gentamicin is slower than in adult animals, are more susceptible to the toxic effect of the drug.

Use half the recommended doses in animals aged up to two weeks.

If the condition of an animal requires longer administration of the drug, the condition of the kidneys is recommended through monitoring of concentrations of urea and creatinine in the blood serum.

The drug should not be used in highly dehydrated animals. The product may have a sensitising effect on the skin causing contact dermatitis. During administration of the drug, protective clothing should be worn and special caution should be exercised. On accidental contact with the drug, the solution should be washed from the skin or the mucous membranes immediately. In the case of a self-injection, a hypersensitivity reaction may occur. After accidental self-injection, immediately seek medical help and show the information leaflet or the package to the physician.  Do not use throughout pregnancy.

Due to the nephrotoxic effect, use carefully in lactation only when the benefit for the mother exceeds the potential risk for the newborn animals. Gentamicin displays cross-resistance with other amino glycosides. It has a synergic effect with β-lactam antibiotics (especially ampicillin and benzyl penicillin) on enterococci, staphylococci and streptococci. It also has a synergic effect with vancomycin and rifampicin on streptococci and staphylococci. Cephalosporins and some diuretics intensify nephrotoxicity and ototoxicity of the drug. Therefore, the drug cannot be administered in combination with cephalotin, cephaloridine, etacrynic acid, mannitol and furosemide. Its simultaneous use with vancomycin intensifies nephrotoxicity of both drugs.

A combination with cisplatin reduces excretion of gentamicin thus posing a risk of nephrotoxicity and hypomagnaesemia. The preparation should not be mixed with solutions of penicillins with a wide spectrum because it may lead to inactivation of amino glycoside. The simultaneous use with amphotericin B, cyclosporine, cisplatin, methoxyflurane, acyclovir and non-steroid anti-inflammatory drugs may result in renal damage. Gentamicin administered in general anaesthesia in combination with cyclopropane may cause apnoea. After gentamicin overdose, functional disorders of the kidneys, neuromuscular block, impaired hearing may occur - the administration of the drug should be discontinued.

Do not use with other antibiotics, strong diuretics and potentially nephro- and ototoxic drugs.

Do not use in combination with anaesthetics or myorelaxants.

Unused veterinary medicinal product or its waste should be neutralised in accordance with appropriate regulations.

2 years 

Available packages
Orange glass bottles  vol. 50 ml, packed individually in a cardboard box.

Other information
Exclusively for animals
Prescription-only-medicine (POM)
For use under the supervision of a veterinary surgeon

 More details

Name Description
Place of Origin: Poland

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 24-100 Pulawy, Arciucha 2 NIP 716-11-26-796 Biowet Pulawy Ltd.,Poland, Europe
 4 years, 8 months ago

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